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Objective: The objective of the study is to investigate the antibacterial activity of African giant land snail (Archachatina marginata) slime against some bacteria isolated from various types of wound.
Methodology: Six (6) bacterial isolates (Staphylococcus aureus, Methicillin Resistant Staphylococcus aureus (MRSA) Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa and Klebsiella sp) isolated from wound sample of patient obtained from Microbiology Department of Muhammad Abdullahi Wase Specialist Hospital Kano were involved in the study. The antibacterial activity of the slime extract was determined using agar well diffusion method while minimum inhibitory concentration of the slime was determined using broth dilution technique.
Results: The result showed that higher activity was shown by E. coli with average zone of inhibition of 15.2 mm, followed by Klebsiella sp (14.2 mm), Proteus mirabilis (13.3 mm), Pseudomonas aeruginosa (13.0 mm) and least activity was shown by Staphylococcus aureus (09.1 mm). No activity was shown by Methicillin Resistant Staphylococcus aureus (MRSA). There is no statistical difference in the activity of the slime against the test isolates (p<0.05).
Â Conclusion: It is concluded that the slime of A. marginata contain antibacterial agents.
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