Main Article Content
Objective: In this study, evaluation of physicochemical, phytochemical parameters, and antioxidant activity of S. barbata was done to ensure the quality of plant material and analysis of the phytoconstituents qualitatively as well as quantitatively responsible for its pharmacological values.
Material and methods: The physicochemical parameters such as foreign matter, moisture content, ash values, bitterness test, swelling index, foaming index, and the extractive values in different solvents were determined according to WHO guidelines, which helps in ensuring the safety and purity of the sample. Further, qualitative and quantitative analysis of phytochemicals such as alkaloids, flavonoids, tannins, anthraquinones, glycosides, oils and fats, and saponins were done as per standard methods.
Results: In the present study, the results obtained evident that hydroethanolic extract of S. barbata contains medicinally important bioactive compounds, which justifies its traditional use and also contributes to therapeutic importance as well as anti-oxidant potential.
Conclusion: The numerical standards and pharmacognostic data obtained from the physicochemical analysis could be useful in the proper identification and compilation of monographs of S. barbata.
Selvamaleeswaran P, Wesely EG, Johnson M, Velusamy S, Jeyakumar N. The effect of leaf extracts of Clitoria ternatea Linn against the fish pathogens. Asian Pac J Trop Med 2010; 3(9):723-6.2. Bannerman RH, Burton J and Ch'en WC. Traditional medicine and health care coverage: a reader for health administrators and practitioners, The Cross-Disciplinary Perspectives of Management: Challenges and Opportunities, 1983: 342.
Chaudhari RK and Girase NO. Determination of soluble extractives and physico-chemical studies of bark of Sesbania sesban (L) Merr. J Chem Pharm Res 2015, 7(8): 657-660.
Ahmad M, Khan MA, Rashid U, Zafar M, Arshad M, and Sultana S. Quality assurance of herbal drug valerian by chemotaxonomic markers. Afr J Biotechnol 2009; 8(6): 1148-1154.
Sachan AK, Vishnoi G and Kumar R. Need of standardization of herbal medicines in modern era. Int J Phytomedicine 2016; 8 (3): 300-307.
EMEA, Quality of Herbal Medicinal Products Guidelines, European Agency for the Evaluation of Medicinal Products (EMEA), London. 1998.
Archana A and Anubha K. Standardization of herbal drugs: an overview. Int Res J Pharm 2011; 12(2): 56-60.
World Health Organization. Guidelines for the Assessment of Herbal Medicines, WHO Technical Report Series, World Health Organization, Geneva; 1996a; 863.
Gordon and David. Natural product drug discovery in the next millennium. Pharm Bio 2001; 39 (1): 8-17.
Saxena M, Saxena J, Nema R, Singh D and Gupta A. Phytochemistry of Medicinal Plants. J Pharmacog Phytochem 2013; 1 (6): 168- 182.
Tripathi AK and Kohli S. Pharmacognostic and phytochemical studies on the flowers of Punica granatum. Int J Pharm Res Dev 2012; 3(11): 1-7.
Nonita PP and Mylene MU. Antioxidant and cytotoxic activities and phytochemical screening of four Philippine medicinal plants. J Med Plant Res, 2010; 4: 407-414.
UNESCO, FIT/504-RAF-48 Terminal Report: Promotion of Ethnobotany and the Sustainable Use of Plant Resources in Africa, Paris, France, 1998, 60.
World Health Organizational. Quality Control Methods for Medicinal Plant Materials, Geneva, Switzerland: WHO; 1998: 128.
Brain KR and Turner TD. The practical evaluation of Phytopharmaceuticals, Wright science technical, Bristol Britain; 1975; 1: 144.
Evans WC. Trease Evans Pharmacognosy, London: WB Saunders Ltd, 1966; 14: 119- 159.
Harborne JB. Phytochemical Methods, Chapman and Hall Ltd., London; 1973; 49-188.
Kokate CK, Purohit AP and Gokhale SB. The Text Book of Pharmacognosy, Nirali prakashan, Pune; 2006: 67.19. Siddiqui AA and Ali M. Practical Pharmaceutical Chemistry. CBS Publishers and Distributors, New Delhi; 1997; 1: 126-131.
Yadav RN and Agarwal M. Phytochemical analysis of some medicinal plants. J Phytologic Res 2011; 3(12): 10-14.
Ajuru1 MG, Williams LF and Ajuru G. Qualitative and Quantitative Phytochemical Screening of Some Plants Used in Ethnomedicine in the Niger Delta Region of Nigeria. J Food Nutr Sci 2017; 5(5): 198-205 22. Pourmorad F, Hosseinimehr SJ and Shahabimajd N. Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. Afr J Biotechnol 2006; 5: 1142-1145.
Khaabadi SS, Deore SL and Baviskar BA. Experimental Phytopharmacognosy: A Comprehensive Guide. Nirali prakashan, Pune; 2011; 4(13).
Tambe VD and Bhambar RS. Estimation of Total Phenol, Tannin, Alkaloid and Flavanoid in Hibiscus Tiliaceus Linn. Wood Extracts. J Pharmacog Phytochem 2014; 2(4): 41-47.
Sultana M, Verma PK, Raina R, Prawez S and Dar MA. Quantitative Analysis of Total Phenolic, Flavanoids and Tannin Contents in Acetone and n- Hexane Extracts of Ageratum conyzoides, Int J PharmTech Res 2012; 4(3):996-999.
Alhakmani F, Kumar S and Khan SA. Estimation of total Phenolic content, in- vitro Antioxidant and anti inflammatory activity of Moringa Oleifera. Asian Pac J Trop Biomed 2013; 3(8):623- 627.
Jia ZS, Tang MC and Wu JM. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem 1999; 64: 555–559.
Li H, Wang Z and Liu Y. Review in the studies on tannins activity of cancer prevention and anticancer. J Chi Med Mat 2003; 26: 444–448.
Hong-Xi XU, Min WAN, Hui DONG, Paul Pui-Hay BUT and Lai Yeap FOO. Inhibitory Activity of Flavonoids and Tannins against HIV-1 Protease. Bio Pharm Bull 2000; 23: 1072-1076. 30. Aryal S, Baniya MK, Danekhu K, Kunwar P, Gurung R and Koirala N. Total Phenolic Content, Flavonoid Content and Antioxidant Potential of Wild Vegetables from Western Nepal. Plant (Basel) 2019; 8(4): 96. 31. Qiong Chen, Rahman K. Wang SJ, Zhou S and Zhang H, Scutellaria barbata: A review on chemical constituents, pharmacological activities and clinical applications. Curr Pharm Des 2020; 26: 160. 32. Pietta PG. Flavonoids as antioxidants. J Nat Prod 2000; 63(7):1035-1042.