Main Article Content

Syed Javeed
A Hemanth
N.M. Vageesh
T Achuth Kumar


Ropinirole Hydrochloride is an Anti-Dyskinesia Agents used in the management of Parkinson's Disease. Present work aimed at preparing quick onset of action which is beneficial in hypertension, aiding in the enhancement of bioavailabity and is very convenient for administration without the  problem  of  swallowing  and  using  water.  The  film  were  prepared  by  using  polymers  such  as Hydroxy propyl methyl cellulose (HPMC) E3, E5, E15 by a solvent casting method.  They  were  evaluated  for  physical  characteristics  such  as  Thickness, Weight Variation, Disintegration time, Drug content, Tensile strength, % Elongation, Folding Endurance and Invitro Dissolution Studies give satisfactory results. The in vitro dissolution time of the optimized  batch  F5  was  found  to  be  99.04%.  The  optimized  batch  in vitro disintegration time was  found  to  15 sec.


Download data is not yet available.

Article Details

How to Cite
Javeed, S., Hemanth, A., Vageesh, N., & Kumar, T. A. (2018). FORMULATION AND IN VITRO EVALUATION OF ORAL DISINETGRATING FILM OF ROPINIROLE HYDROCHLORIDE FOR THE TREATMENT OF PARKINSON’S DISEASE. Innovat International Journal Of Medical & Pharmaceutical Sciences, 3(1).
Original Article(s)


Aditya D, Nagarsenkar M Formulation and evaluation of Fast dissolving Film for delivery of Triclosan to the oral cavity. AAPS Pharma ScienceTechnology.2008; 9, 2:10

Arya A, Chandra A. Sharma V, Pathak K. Fast dissolving oral films: An innovative drug delivery system and dosage form. International Journal Chemical Technical Res 2010; 2: 576-583.

Anand V, Kataria M, Kukkar V, Saharan V, Choudhury PK. The latest trends in the taste assessment of pharmaceuticals. Drug Discovery Today 2007; 12: 257-265.

Arya A, Chandra A, Sharma V, Pathak K, Fast dissolving oral films: An Innovative Drug Delivery system and Dosage form. Int. J. Chem. Tech. Res. 2010, 2: 576-583.

Banker GS. Film coating theory and practice. Journal Pharma Science 1966; 55: 81†89.

Barnhart SD. Thin film oral dosage forms in Modified release. Drug delivery Techology 2007; 1: 34-35.

Barnhart S, Rathborne M, Hadgraft J, Roberts M, Lane M. Thin film oral dosage forms in Modified release drug delivery technology. 2nd ed., Drugs and the Pharmaceutical Science; 209-216.

BasaniGavaskar, SubashVijaya Kumar, Guru Sharan, Y.MadhusudhanRao, Overview on Fast Dissolving Films, International Journal of Pharmacy and Pharmaceutical Sciences, 2010, 2 (3): 29-33.

Bess WS, Kulkarni N, Ambike SH, Ramsay MP, Fast dissolving Orally Consumable Solid Film Containing a Taste Masking Agent and Pharmaceutically Active Agent at different weight ratio, 2006 Jun 27.

BhupinderBhyan, SaritaJangra, MandeepKaur, Harmanpreet Singh, Orally Fast Dissolving Films: Innovations in Formulation and Technology, International Journal of Pharmaceutical Sciences Review and Research, 2011, 9(2): 50-56.

Borsadia BB, Osborne JA. Quick dissolving films: A novel approach to drug delivery. Drug delivery Technology - Article index.

Brown D, Orally disintegrating tablets: Taste over speed. Drug Tech, 2001, 58-61.

Chang RK, Guo X, Burnside BA, Couch RA. Fast dissolving tablets. Pharma Tech 2000; 24(6): 52-58.

Chapdelaine AH, Zyck DJ, Dzija MR. Edible film formulations containing maltodextrin. US Patent. 2004.

Coppens KA, Hall MJ, Mitchell SA. Hypromellose, Ethyl cellulose and Polyethylene oxide used in hot melt extrusion. Pharmaceutical Technology 2005; 3: 1-6.

Similar Articles

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)